Hazardous Drug Compositions and Health Hazards

Today is the world of drugs and medicines, ashealthcare organizations such as OSHA and NIOSH
these have been the most inevitable and essentialhave published drug handling guidelines to reduce
requirements of our life. These drugs are thethe extent of exposure to these drugs in the
most amazing discovery of man towardsworkplaces. Workers and staffs handling these
mankind. They possess ultimate capability todrugs are prone to the risks of being in direct
withstand dreadful diseases such as cancer andcontact with them during their preparation,
tumor. Having such tremendous success and hugeadministration, monitoring, transfer and disposal
achievements of these drugs in the field ofprocesses. To limit workers probability of
medical science, what made healthcareexposure, several protective equipments such as
organizations to be worried about the occupationalclosed systems, biological safety cabinets, etc. has
exposure to most of these drugs?been designed. They are instructed to use
Studies conducted on various drug compositionspersonal protective equipments such as masks,
have shown that the major constituents used ingloves, gowns, lab. Courts etc. and take
manufacturing drugs are several chemicalnecessary precautionary measures while
substances which are hazardous in nature. Whenmonitoring these drugs.
such chemicals including antineoplastic agents,These safety guidelines calls different healthcare
cytotoxic agents, antiviral and immunosuppressiveindustries such as hospitals, medical clinics, drug
agents are used in drug preparation, then themanufacturing plants and many other sectors
drugs are designated as hazardous drugs. As alldealing with pharmaceuticals, to recruit well trained
these chemicals have inherent toxicities tomedical staffs and employees. Further all these
produce health disorders when exposed to lives,sectors should have facilities of advanced training
healthcare settings are looking for alternatives foron handling newly designed safety equipments and
their minimal use in useful drug preparation.recently developed treatment techniques. They
Surveys and research works are still going on forshould also incorporate medical surveillance
new and effective solutions against theseprograms to monitor the level of exposure of
hazardous drugs. As the discovery of betterthese drugs in workers.
substitutes will definitely take time so, major